dfh=open('allc_All_cluster_CpG.txt_strand_integrate.txt','r')
rfh=open('allc_All_cluster_CpG.txt_strand_integrate_Fixed.txt','w')
rfh.write(dfh.readline())
for i in dfh:
	line=i.split()
	ID=line[0].split('_')
	if ID[3]=='-':
		rfh.write(str(int(ID[0])-1)+'_'+ID[1]+'_'+str(int(ID[2])-1)+'_+_CG'+'\t'+'\t'.join(line[1:])+'\n')
	else:
		rfh.write(i)